What is a common sign of organophosphate poisoning?

Organophosphate poisoning is characterized by the inhibition of the enzyme acetylcholinesterase, which leads to an accumulation of acetylcholine at neuromuscular junctions and synapses. This build-up causes a range of cholinergic symptoms due to overstimulation of the parasympathetic nervous system.

Vomiting is a common sign of organophosphate poisoning as it results from increased gastrointestinal activity due to the excess acetylcholine. As the poison affects the autonomic nervous system, it can provoke symptoms like nausea and increased salivation, both of which can lead to vomiting.

Other symptoms associated with organophosphate poisoning often include diarrhea, miosis (constricted pupils), and bradycardia (slowed heart rate). However, in this context, vomiting serves as a notable indicator of the poisoning, highlighting the increased secretory activity in the gastrointestinal tract.